Clara Barrus was a Port Byron native who went onto to become an early woman physician and author. Wikipedia says;
“In 1901, [John] Burroughs [the early naturalist] met an admirer, Clara Barrus (1864–1931). She was a physician with the state psychiatric hospital in Middletown, N.Y. Clara was 37 and nearly half his age. She was the great love of his life and ultimately his literary executrix. She moved into his house in 1917.”

Here she sits, most likely looking out over the Hudson Valley, where she and John lived.